Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIRA All Species: 32.42
Human Site: S876 Identified Species: 44.58
UniProt: P54198 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54198 NP_003316.3 1017 111835 S876 D F R S S L P S Q D A M L C S
Chimpanzee Pan troglodytes XP_001165585 1017 111787 S876 D F R S S L P S Q D A M L C S
Rhesus Macaque Macaca mulatta XP_001112873 1138 124408 S997 D F R S S L P S Q D A M L C S
Dog Lupus familis XP_543550 1017 111618 P876 D F R S S L P P Q D A M L C S
Cat Felis silvestris
Mouse Mus musculus Q61666 1015 111748 S874 D F R N S L P S Q D A M L C S
Rat Rattus norvegicus NP_001129232 1015 111665 S874 D F R N S L P S Q D A M L C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P79987 1019 112055 S882 D F R S S L P S Q E A M L C S
Frog Xenopus laevis Q8QFR2 1013 112021 S872 D Y R S C M P S Q D A V M C S
Zebra Danio Brachydanio rerio XP_696478 1010 111223 S869 D F R N C L S S Q D V L G S M
Tiger Blowfish Takifugu rubipres O42611 1025 111838 N884 D F R N C L P N Q D A P M S S
Fruit Fly Dros. melanogaster O17468 1047 113397 S894 P P Q Q K T A S S A G S S P R
Honey Bee Apis mellifera XP_001122939 838 91355 T715 L Q E G L F R T A G N T F P N
Nematode Worm Caenorhab. elegans Q09589 935 103412 P812 G T T N S A G P L V R L L K R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q32SG6 964 105548 S841 L E N Q L A S S L A L K S A Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXN4 1051 115544 D897 R F L A R E A D E S R L R E V
Baker's Yeast Sacchar. cerevisiae P32479 840 93871 K717 A I G S K D C K C W C L A S A
Red Bread Mold Neurospora crassa Q7RZI0 1035 112420 Y875 V S A G I I P Y L E R H T T T
Conservation
Percent
Protein Identity: 100 99.9 88.4 96.5 N.A. 95.7 95.5 N.A. N.A. 86 78 69.8 67.7 31.1 40 26.5 N.A.
Protein Similarity: 100 99.9 88.9 98 N.A. 97.5 97.7 N.A. N.A. 93.1 88.5 83.2 81.3 48 55.1 46.1 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 66.6 46.6 60 6.6 0 13.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 100 93.3 60 80 13.3 13.3 26.6 N.A.
Percent
Protein Identity: N.A. 25.6 N.A. 25 22.4 25.9
Protein Similarity: N.A. 43.7 N.A. 43.3 41.2 45.8
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. 6.6 N.A. 26.6 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 6 0 12 12 0 6 12 53 0 6 6 6 % A
% Cys: 0 0 0 0 18 0 6 0 6 0 6 0 0 48 0 % C
% Asp: 59 0 0 0 0 6 0 6 0 53 0 0 0 0 0 % D
% Glu: 0 6 6 0 0 6 0 0 6 12 0 0 0 6 0 % E
% Phe: 0 59 0 0 0 6 0 0 0 0 0 0 6 0 0 % F
% Gly: 6 0 6 12 0 0 6 0 0 6 6 0 6 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % H
% Ile: 0 6 0 0 6 6 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 12 0 0 6 0 0 0 6 0 6 0 % K
% Leu: 12 0 6 0 12 53 0 0 18 0 6 24 48 0 0 % L
% Met: 0 0 0 0 0 6 0 0 0 0 0 42 12 0 6 % M
% Asn: 0 0 6 30 0 0 0 6 0 0 6 0 0 0 6 % N
% Pro: 6 6 0 0 0 0 59 12 0 0 0 6 0 12 0 % P
% Gln: 0 6 6 12 0 0 0 0 59 0 0 0 0 0 6 % Q
% Arg: 6 0 59 0 6 0 6 0 0 0 18 0 6 0 12 % R
% Ser: 0 6 0 42 48 0 12 59 6 6 0 6 12 18 53 % S
% Thr: 0 6 6 0 0 6 0 6 0 0 0 6 6 6 6 % T
% Val: 6 0 0 0 0 0 0 0 0 6 6 6 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % W
% Tyr: 0 6 0 0 0 0 0 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _